The factors influencing a fungus and its development

Far not always getting on a skin, funguses are capable to cause disease. The same fungus causes disease in one people, and at others - is not present. A susceptibility to fungal flora at people different. Thus, the course of a disease a fungus depends not only on patogenicity and virulence of the originator (ability of a fungus to take root and cause disease), so, and even in a greater degree, from a status of a resistance (ability to resist to an infection) an organism of the person. Despite of an abundance of funguses in medium surrounding the person, only few of them possess the expressed patogenicity. The majority of associates us funguses are conditionally pathogenic and one hit of pathogenic funguses in an organism insufficiently for a course of a disease. Presence of so-called contributing factors, readiness of an organism for development of mycotic process is necessary.

The most essential factor of development of fungal diseases of a skin is the age.
It is known, that a microsporia, known to wider population under the name « shearing deprive » amazes basically children of preschool and younger school age and very seldom develops at adults.

Other group of fungal diseases - stop and a fungus of nails, on the contrary, amaze mycosises mainly adult and seldom enough meet at children, that as has the explanation and is bound to age changes РН of a skin, thickness and structure of a cornual layer of a false skin, weakening of immune protection and a resistance of a skin on a background of diseases developing with the years.

Very much for development of fungal disease the disturbances of a metabolism bound to an obesity, other endocrine frustration and first of all with a diabetes mellitis, diseases of adrenals, a thyroid gland, diseases of the gastrointestinal tract, accompanied disturbances of digestion and an absorption of nutrients have great value.

Disturbance of power maintenance and disadvantage of substances of cells necessary for construction are the reason of structural changes of a skin and disturbance of its function and function of immune system. And if to consider, that one of the basic functions of a skin is barrier, and together the skin and immune system are called to protect our organism from introduction of infectious agents including pathogenic funguses, there is clear a role of the listed factors in development of fungal diseases of a skin.

Besides as a result of the metabolic frustration, many of the listed diseases are accompanied by decrease of acidity of a skin and shift РН of a skin in the alkaline party that weakens its barrier function due to creation of favorable conditions for introduction and development of a fungal infection.

Overwork, smoking, abusing alcohol, long application of the antibiotics, insufficient delivery, anemia, HIV-infection increase risk of development of mycosises depression of immunity which reason can be stress.

The probability of development of fungal diseases during pregnancy and during the puerperal period increases. This period of a life of the woman is accompanied by natural weakening of immunity which is aggravated with an anemia as a result of a hemorrhage in labors, at the sleepless nights, alarm for the newborn, deficiency of nutrients and vitamins even at the high-grade delivery, developing as a result of feeding the child by milk.

Circulations accompanied by disturbances and metabolic processes in a skin which result is disturbance of its structure and depression of a resistance in relation to a fungal infection contribute to development of fungal diseases of a skin of disease of vessels and the peripheric nervous system.

For development of mycotic process traumas have great value. The intact skin of the healthy adult person very effectively protects our organism from an external infection as it is practically impenetrable for pathogenic microorganisms including pathogenic funguses. Damage of a skin is accompanied by change of its structure and weakening of a local resistance and facilitates overcoming this effective natural barrier, playing a role of " entrance hiluses » for an infection. Very often the fungus of nails begins with a trauma of a nail plate as a result of pressure of close footwear, bruises, attritions.

© Ramzaj
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